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Ketoconazole

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(Treatment for Fungal infections)

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What is Ketoconzole:

Ketoconazole is an antifungal medication. It is like an antibiotic but is used to treat fungal infections

Ketoconazole is used to treat yeast infections of the mouth, throat, and esophagus; fungal infections throughout the whole body; and serious fungal infections of the skin and nails.

Ketoconazole may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of ketoconazole?

If you experience any of the following serious side effects, stop taking ketoconazole and seek emergency medical attention or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or
liver damage (pale stools, yellowish skin or eyes, abdominal pain, unusual fatigue, or dark urine).

Other, less serious side effects may be more likely to occur. If you experience any of the following side effects, continue to take ketoconazole and talk to your doctor:

nausea, vomiting, or abdominal pain;
diarrhea
headache;
dizziness;
fatigue; or
itching

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect ketoconazole?

Do not take ketoconazole if you are taking any of the following drugs:
· astemizole (Hismanal),
· cisapride (Propulsid), or
· triazolam (Halcion) or midazolam (Versed).

Dangerous or life-threatening events may occur if ketoconazole is taken with any of the medicines listed above.

efore taking ketoconazole, tell your doctor if you are taking any other medicines, especially any of the following:
· cyclosporine (Sandimmune, Neoral);
· tacrolimus ((Prograf);
· methylprednisolone (Medrol, others);
· antacids;
· cimetidine (Tagamet, Tagamet HB), nizatidine (Axid, Axid AR), famotidine (Pepcid, Pepcid AC), or ranitidine (Zantac, Zantac 75);
· omeprazole (Prilosec), lansoprazole (Prevacid), or rabeprazole (Aciphex);
· digoxin (Lanoxin, Lanoxicaps);
· warfarin (Coumadin);
· phenytoin (Dilantin, others);
· rifampin (Rifadin, Rimactane); or
· an oral diabetes medicine such as glipizide (Glucotrol), glyburide (Diabeta, Micronase, Glynase), tolbutamide (Orinase), tolazamide (Tolinase), chlorpropamide (Diabinese), and others.

You may not be able to take ketoconazole, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with ketoconazole or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.